Physician assistant
Casey Howe, PA-C
Locations: Des Moines (Downtown), Ankeny, Johnston, Norwalk, Pleasant Hill

About Casey
Casey Howe, PA-C, is a physician assistant specializing in knee and hip injuries with a focus on total joint reconstruction. Originally from Elvira, Iowa, Casey’s deep-rooted passion for athletics and personal experience with sports injuries inspired his path into orthopedic medicine. As a former four-sport high school athlete and collegiate football player at Simpson College, Casey experienced firsthand the challenges of recovering from multiple ACL injuries. These experiences, along with the care he received from orthopedic teams, sparked his commitment to helping others return to the activities they love.
He holds a Bachelor of Arts in Athletic Training from Simpson College, a Master’s in Kinesiology from the University of Florida, and a Master of Science in Physician Assistant Studies from Des Moines University. During his time at the University of Florida, Casey served as a Graduate Assistant Athletic Trainer, providing sideline care to a variety of club and intramural sports including hockey, lacrosse, wrestling, and football.
Casey’s approach to patient care is grounded in active listening and meaningful conversations. He believes building trust is key to both accurate diagnosis and effective treatment. He finds the greatest reward in seeing patients go from living with debilitating arthritis to returning pain-free and able to enjoy new activities and adventures they never thought possible.
Outside of work, Casey and his wife stay busy cheering on their three children in a variety of sports and extracurricular activities. When time allows, you’ll find him on the golf course enjoying the outdoors and perfecting his swing.
Des Moines University; Des Moines, IA
Master’s Degree
University of Florida; Gainesville, FL
Undergrad
Simpson College; Indianola, IA
Supervising Physician
Patient Reviews
July 4, 2025
Casey is a gentleman and a scholar. He is very professional and easy to talk to, and I feel very comfortable with this expertise.
Patient Submitted Review
June 14, 2025
Great visit with a great guy! Casey is very knowledgeable, encouraging, and easy to talk to. I highly recommend this practice and provider.
Patient Submitted Review
June 13, 2025
Convenient and super friendly staff! Casey went out of his way to help me coordinate care with my families crazy schedule coming up
Patient Submitted Review
May 16, 2025
Casey is a great P.A. He has been not only highly professional but also very interested and caring in his care for my condition. A definite asset to Iowa Ortho!
Patient Submitted Review
May 8, 2025
Very good experience with Casey, he was easy to talk to, very supportive of my decision to continue with what I feel I can do. And I definitely will be calling when I need follow up!
Patient Submitted Review
April 28, 2025
Casey greeted my husband and I with professionalism and a warm handshake. Immediately gave a feeling of calm! Very informative and offered options other than surgery which was appreciated, but at my point in this journey, I knew surgery was where I was at. Skillfully and painlessly injected both knees. Glad to hear he will be in the surgical team! Thank you Casey!!
Patient Submitted Review
April 26, 2025
Casey was very comforting and his personality was pure kindness. HE SHARED GOOD NEWS THAT MY KNEE REPLACEMENT 19 years ago IS STILL IN TACT. Thank you Casey!
Patient Submitted Review
April 24, 2025
I am very happy with the care I have received from Casey Howe. He has been so thorough, caring, and pleasant to work with. I couldn’t be happier!
Patient Submitted Review
March 20, 2025
Casey and Dr. Mahoney are #1 in my book. Nice to see people that appreciate there jobs like those two. Great work guys.
Patient Submitted Review
March 1, 2025
I had my 1 yr follow up for my knee replacment with Casey Howe. WOW! I can’t say enough about how I love Casey Howe and Dr Mahoney and their staff. They did a fabulous job on my knee and recovery was great. Casey always takes time to go over everything with me and answers any questions I have. Believe me, I had a lot of questions a year ago before surgery. Casey How is 5 stars in my book. He is an awesome PA and knows his stuff.
Patient Submitted Review
February 27, 2025
Casey Howe was very informative and direct in a very kind way. He gave me all the time I needed to ask questions. Highly recommend.
Patient Submitted Review
February 16, 2025
I appreciate the time Casey takes to get to know his patients and their medical concerns. He doesn’t rush and takes the time to discuss treatment options.
Patient Submitted Review
January 30, 2025
Casey listened to my concerns and what was going on, he really cared and was supportive about a treatment plan that is realistic to my life and feelings. Gave me hope for a smoother outcome for my knees!
Patient Submitted Review
November 24, 2024
Tim Van Ginkel had procedure done with Casey went exceptionally well. Explained options well in detail so I understood it.
Patient Submitted Review
October 12, 2024
Dr. Howe was very knowledgeable, presented options for my hip issue and was relatable. He also offered follow up.
Patient Submitted Review
April 9, 2024
Have nothing but positive things to say about Casey J. Howe, PA he explains clearly what’s going on and cares about the well being of the patients.
Patient Submitted Review
November 19, 2022
I have been well taken care of by Dr, Craig Mahoney and his. Assistant, Casey Howe. They have been kind and caring before, during and after knee replacement surgery. I recommend them highly!
Patient Submitted Review
October 16, 2022
You, Casey Howe, Dr. Craig Mahoney, and your team are my heros! Two successful knee replacements!!! I am so thankful for you…can’t say enough! You all have been amazing. THANK YOU!!!
Patient Submitted Review
October 14, 2022
Highly recommend Casey J Howe and Iowa Ortho team. Preparing for knee surgery and so thankful for his experience in this process.
Patient Submitted Review
October 8, 2022
Casey Howe is always so polite and listens well and makes you feel comfortable and relaxed. He is very knowledgeable.
Patient Submitted Review
May 28, 2022
Iowa Ortho has always done an excellent job for me; both hips replaced and right knee replacement!:)
Patient Submitted Review
April 15, 2022
Very happy with Dr Casey. Tells me everything so I understand. Has a wonderful bed side manner. Very happy with results. Thank you
Patient Submitted Review
February 26, 2022
I am very satisfied and pleased with work of Dr.Mahoney and Dr. Howe. They diagnosed my problem and fixed it. Which relieved my severe pain. I am able to walk normal through the day.
Patient Submitted Review
February 25, 2022
Casey J Howe, is a amazing Ortho PA-C. He takes his time with you to explain what comes next. He just listens, has compassion for his patients. I’m grateful he is my PA-C!
Patient Submitted Review
January 29, 2022
I’ve been working with Iowa Ortho for just over two years. Casey Howe and Dr. Craig Mahoney have guided me through miserable times with an arthritic knee to the point where I have just had total knee replacement. I totally trust their judgment and appreciate their candor, competence, and support. If you want no-nonsense care, provided by professionals, Dr. Mahoney and his staff should be your first choice.
Patient Submitted Review
December 20, 2021
Got there checked in waited 5 minutes at the most then called back. Casey J. Howe, PA-C came in discussed my case gave me my shots. Very friendly talked in a way you understood what he was talking about knows how to give with little pain.
Patient Submitted Review
September 9, 2021
Enjoyed meeting Casey Howe, PA-C at Iowa Orthopedics Laurel Street office. If you need orthopedic services for yourself, or a loved one, I highly recommend having him on your team. Thanks.
Patient Submitted Review
August 20, 2021
I was very impressed with Casey and the time he took to explain things to me and also the care he gave with the injection in my knee. He answered all my questions and never made me feel rushed at all. The wait time was negligible. I was very impressed overall.
Patient Submitted Review
July 31, 2021
Casey and Craig Mahoney were my surgeons and physicians during my right knee replacement surgery. My surgery and care were exceptional. So very thankful for their professional skill and the heart of cate they showed me.
Patient Submitted Review
July 31, 2021
I appreciate the excellant care provided by Casey Howe, PA-C. He is pleasant and easy to talk with and provides answers to my questions. The whole staff is very friendly and able to decrease a patient’s anxiety. I would highly recommend their care.
Patient Submitted Review
July 25, 2021
First of all there was no waiting. Casey was very nice and took the time to answer my questions. He gave me several options to consider which I appreciate. I highly recommend anyone needing orthopedic care to make an appointment with Casey Howe.
Patient Submitted Review
July 17, 2021
I have seen Casey for knee pain & treatment for many years. I always get the best care, and I feel like I’m the only patient in the building at the time. He’s very attentive, respectful to my needs, and gives me all the time that I need. He’s the best!
Patient Submitted Review
July 16, 2021
I am very pleased with Dr Casey J Howe he listened to me about my pain and I enjoy that he that’s the time for me Thanks so much and God Bless you
Patient Submitted Review
June 22, 2021
On time appointment. Very through exam. Explained results of exam. Provided an on going plan to fix my pain issues. Would recommend this clinic to anyone.
Patient Submitted Review
June 11, 2021
Casey is always professional, but ver caring. He takes time to explain things thoroughly. Very cheerful and happy.
Patient Submitted Review
June 8, 2021
Casey was thorough when discussing options, listened well, and was very encouraging! Great visit with him. Thanks, Casey!
Patient Submitted Review
May 27, 2021
I have always had very great service at Iowa Ortho. Would recommend them to any one and Casey is great. Dr. Mahoney is a very good dr. They make a great pair.
Patient Submitted Review
May 22, 2021
He’s very kind and helpful. Discussed all options that could be done and listens well to what you think and feel. Working in healthcare myself I can see Casey going far in his work. He works with a great Doctor, Dr Mahoney. Both are very caring about what they do.
Patient Submitted Review
May 8, 2021
Very clean. Both my doctor and his PA we’re both very nice and answered my questions perfectly didn’t have to wait long.
Patient Submitted Review
May 7, 2021
Thanks to Dr Howe and Dr Mahoney for their help with my problem. Great job to them and the staff. Thanks for the great service.
Patient Submitted Review
April 8, 2021
Dr Mahoney and his staff at Iowa Ortho completed my knee replacement surgery recently. They are professional, competent, knowledgeable, caring and experienced. Casey Howe handled my follow-up appointment in the same manner. I highly recommend iowa Ortho.
Patient Submitted Review
February 27, 2021
Very great place to help you .Dr. Casey is a awesome doctor he listen to you and your concerns about your well being .He is so professional …Tries to do what he can to help you in anyway.Had a total knee replacement in December .My knee is doing good with everyday to come …I would recommend him to help with you need a doctor.. You will not be disappointed in him..Thank you for helping me Dr. Casey. .God bless.
Patient Submitted Review
February 20, 2021
Casey Howe is amazing! He is very personable & willing to listen to your health needs. You will not be disappointed if you schedule a visit with Casey. 😊
Patient Submitted Review
January 14, 2021
They were running a little behind on their appointments, but the care and concern the staff shows is the best.
Patient Submitted Review
January 13, 2021
Casey Howe is one of the BEST medical professionals I’ve ever had the pleasure of being treated by! He always takes plenty of time with me, he answers any questions I may have & he gives me clear instructions for my care. I would definitely recommend him to my family &/or friends for their Ortho needs. Iowa Ortho & Mercy are fortunate to have Casey represent them, he is a true asset to their organizations!
Patient Submitted Review
November 19, 2020
PA Casey is my favorite. He listens, he gives you the time you need and has such a great attitude! Thank you for everything. You and Dr. M make a wonderful team. My new hip says Thank You!!!!!!!!!
Patient Submitted Review
November 3, 2020
Casey is very attentive and listens. He genuinely cares how you are feeling and tries to do everything possible to make sure you are on the right track, before and after surgery. Has a positive attitude and works along side my great surgeon Dr. Mahoney.
Patient Submitted Review
October 29, 2020
I am very pleased each time I go see either Dr. Mahoney or Casey. They are very professional and kind and do everything they can to make me comfortable. I would recomend them to anyone.
Patient Submitted Review
September 26, 2020
Went in to Iowa Ortho for my continued knee osteoarthritis. Casey answered all my questions. He is very knowledgeable about the knee and made me feel a lot better.
Patient Submitted Review
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